When our family went to Legoland recently, Trevor and I posed in front of the entrance sign, like just about everyone else does.
I printed 12 of our photos from the day, including this one, to use for my 2-page layout. When I started arranging the pictures on the page, I realized that the Legoland sign in my photo was large and bold enough to serve as my title. I grouped some colorful accents both above and to the left of the photo to draw the eye. I added a third color grouping by my journaling. It forms a visual triangle that leads right back to the title. I think it works.
To contrast, let me show you a layout with a photo used as a title that doesn't work. This is from our cruise to Hawaii three years ago. Look closely in the middle left where I'm using a photo of a Hawaii sign as my title.
This layout does not work for a number of reasons. The title recedes into the background because it is not large or bold enough. My fussy cut flower accents form a visual triangle, but that triangle doesn't center on the title. There is nothing to lead the eye to the appropriate location. This is a case where I knew I was creating a layout that didn't work, but I couldn't figure out how to fix it and finally just gave up. Now in hindsight, it's so obvious to me why it didn't work!
Using a photo as a title can work well in a multi-picture layout. Just be sure that the title is large and bold enough, then use your embellishments to lead the eye to the title. Have you used a photo as a title? I'd love to see what you made!